Latest SICARIO Trailer and More Promotional Videos Witness the new SICARIO trailer and more promotional videos! The film, directed by Denis Villeneuve (Enemy, Prisoners), stars Emily Blunt, Benicio Del Toro, Josh Brolin, Victor Garber, Jeffrey Donovan, Maximiliano Hernández, Daniel Kaluuya, and Jon Bernthal. SICARIO will be released in select theaters on September 18 and nationwide the 25th. In Mexico, Sicario means hitman. In the lawless border area stretching between the U.S. and Mexico, an idealistic FBI agent is enlisted by an elite government task force official to aid in the escalating war against drugs. Led by an enigmatic consultant with a questionable past, the team sets out on a clandestine journey forcing Kate to question everything that she believes in order to survive.