THE HUMAN CENTIPEDE III (FINAL SEQUENCE) First Full Trailer Witness the first full THE HUMAN CENTIPEDE III (FINAL SEQUENCE) trailer! The last chapter on the saga, directed by Tom Six (The Human Centipede (First Sequence), The Human Centipede II (Full Sequence)), stars Eric Roberts, Tommy ‘Tiny’ Lister, Bree Olson, Dieter Laser, Carlos Ramirez, and Tom Six. THE HUMAN CENTIPEDE III (FINAL SEQUENCE) will be released in limited theaters and VOD on May 22. Taking inspiration from Tom Six’s The Human Centipede films, Governor Hughes enlists the help of Warden Bill Boss and Bill’s charming and devious boyfriend Dwight Butler to create a 500 centipede experiment with the use of prisoners from Boss’ prison.