THE HUMAN CENTIPEDE III (FINAL SEQUENCE) Teaser Trailer Witness the first THE HUMAN CENTIPEDE III (FINAL SEQUENCE) teaser trailer! The saga’s conclusion, directed by Tom Six (The Human Centipede (First Sequence), The Human Centipede II (Full Sequence)), stars Eric Roberts, Tommy ‘Tiny’ Lister, Bree Olson, Dieter Laser, Carlos Ramirez, and Tom Six. THE HUMAN CENTIPEDE III (FINAL SEQUENCE) will be released in theaters on May 22. Taking inspiration from Tom Six’s The Human Centipede films, Governor Hughes enlists the help of Warden Bill Boss and Bill’s charming and devious boyfriend Dwight Butler to create a 500 centipede experiment with the use of prisoners from Boss’ prison.